Conflict of interest can be defined as “A conflict between the private interests and official responsibilities of a person in a position of trust.”In clinical drug trials, conflict of interest usually refers to the situation in which an investigator has a financial relationship (often research funding) with a company whose product the investigator is studying.
There is nothing intrinsically wrong with conflicts of interest; they are virtually ubiquitous in clinical drug trials because so many trials are funded by the manufacturer of the product being studied. The problem is less conflict of interest itself; the problem is that conflict of interest may be a risk factor for scientific misconduct..
Forms of COI:
- Property/ Stock Ownership
Steps to control Conflict of Interest:
- Always disclose!
- Mitigate and manage, where possible
- Modify research design
- Monitor research by independent reviewers
If monitoring is not feasible, you may be required to:
- Discontinue the compensated activity
- Divest self of the financial interest
- Terminate the research