Drug Discovery Process – Part I

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Drug Discovery Process – Part I

Discovery

Typically, researchers discover new drugs through:

  • New insights into a disease process that allow researchers to design a product to stop or reverse the effects of the disease
  • Many tests of molecular compounds to find possible beneficial effects against any of a large number of diseases
  • Existing treatments that have unanticipated effects
  • New technologies, such as those that provide new ways to target medical products to specific sites within the body or to manipulate genetic material

At this stage in the process, thousands of compounds may be potential candidates for development as a medical treatment. After early testing, however, only a small number of compounds look promising and call for further study.

Steps Involved in Drug Discovery

Target identification

Target validation

Lead Discovery

Assay development

Lead optimization

Source: 1, 2

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