The Indian Council for Medical Research (ICMR) has invited research proposals on ‘OMICS’ in health & disease. OMICS refers to a field of study in biological sciences that ends with omics such as genomics, transcriptomics, proteomics, metabolomics, etc.
This call for proposal is primarily for Mission mode projects addressing an integrated approach of genomics (encompassing transcriptomics and epigenomics), proteomics, metabolomics and lipidomics, to gain better understanding of diseases.
Genomics is the most mature of the OMICS fields. In the realm of medical research, genomics focuses on identifying genetic variants associated with disease, response to treatment, or future patient prognosis. Epigenomics focuses on genome-wide characterization of reversible modifications of DNA or DNA-associated proteins, such as DNA methylation or histone acetylation.
Proteomics is used to quantify peptide abundance, modification, and interaction and metabolomics simultaneously quantifies multiple small molecule types, such as amino acids, fatty acids, carbohydrates, or other products of cellular metabolic functions.
The focus areas of the ICMR taskforce initiative are airway diseases, neglected tropical diseases, inborn metabolic disorders, neonatal stunting and life style diseases (obesity, non-alcoholic fatty liver disease and cardio-metabolic disease).
It provides great opportunity and hope to identify biomarkers specific for different cellular processes or disease state along with those indicating efficacious therapeutic intervention.
This discipline integrates genomic, proteomics, metabolomics and lipidomics sciences to get a comprehensive picture/profile of cellular and organismal biology.
Over the last decade ICMR has also supported a large number of PI initiated projects on Genomics of human diseases. Now it is becoming clear that the integration of information from different –OMICS studies can provide scientists and clinicians with a powerful tool to understand the different processes involved in disease development and progression.
The OMICS field has been driven largely by technological advances that have made possible cost-efficient, high-throughput analysis of biologic molecules.
All scientific institutions, including universities, DSIR certified institutes and laboratories are eligible for the proposals.
The last date for submitting the proposals is February 08, 2021.
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